Fighting Disease, 1500–1800
Aligned to the AQA 8145 specification
- Level
- Intermediate
- Reading time
- 6 min
- Published
- 6 July 2026
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Key takeaways
- Between 1500 and 1800, everyday treatment changed slowly: herbs, bleeding and purging continued, exploration brought new remedies such as cinchona (quinine) bark, and 'quacks' sold useless patent medicines.
- The Great Plague of 1665 struck London; people still did not know the true cause, but the government now acted more, ordering quarantine, shutting up infected houses and killing cats and dogs.
- Hospitals changed after c1700: many new voluntary hospitals were built, and their focus shifted from religious care towards treating patients, teaching and improving the training of surgeons and physicians.
- John Hunter (1728–1793) raised the status of surgery by using a scientific, experimental approach, dissecting and collecting thousands of specimens and training surgeons such as Edward Jenner.
- Despite these changes, there was still no understanding that germs cause disease, so treatments remained limited and many people relied on home remedies, wise women and apothecaries.
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Key terms
- Quackery
- The selling of useless or fraudulent medicines and treatments by untrained people making exaggerated claims to cure disease.
- Patent medicine
- A ready-made remedy sold to the public, often by quacks, with secret ingredients and bold but false claims.
- The Great Plague
- A serious outbreak of plague in London in 1665, met with quarantine and other government measures.
- Voluntary hospital
- A hospital funded by charity and wealthy donors, many of which were built in Britain in the 18th century to treat the sick poor.
- Apothecary
- A person who prepared and sold medicines and often gave medical advice, cheaper than a physician.
- John Hunter
- An 18th-century surgeon (1728–1793) who promoted a scientific, experimental approach to surgery and trained Edward Jenner.
Frequently asked questions
Most treatment stayed traditional: herbal remedies, bleeding and purging, based on old ideas about the humours. New ingredients from exploration, such as cinchona bark for fevers, appeared, and 'quacks' sold useless patent medicines with big claims. There was still no idea that germs caused disease.
The Great Plague was a major outbreak of plague in London in 1665. People still did not know the true cause, but the government acted more firmly than during the Black Death, ordering quarantine, shutting up and marking infected houses, banning large gatherings and killing cats and dogs.
John Hunter (1728–1793) helped make surgery more scientific and respected. He studied anatomy through dissection, collected thousands of specimens, insisted on careful observation and experiment, and trained a new generation of surgeons, including Edward Jenner.
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