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Intermediate

Fighting Disease, 1500–1800

HP Britain: Health and the people c1000–present

Aligned to the AQA 8145 specification

Level
Intermediate
Reading time
6 min
Published
6 July 2026
On this page
  1. 1.Old Cures and New: Treating Disease in the Early Modern Period
  2. 2.Quackery: Medicine for Profit
  3. 3.The Great Plague of 1665: Progress in Response?
  4. 4.Hospitals: From Care to Treatment
  5. 5.John Hunter: Making Surgery Scientific
  6. 6.Common Exam Mistakes

Key takeaways

  • Between 1500 and 1800, everyday treatment changed slowly: herbs, bleeding and purging continued, exploration brought new remedies such as cinchona (quinine) bark, and 'quacks' sold useless patent medicines.
  • The Great Plague of 1665 struck London; people still did not know the true cause, but the government now acted more, ordering quarantine, shutting up infected houses and killing cats and dogs.
  • Hospitals changed after c1700: many new voluntary hospitals were built, and their focus shifted from religious care towards treating patients, teaching and improving the training of surgeons and physicians.
  • John Hunter (1728–1793) raised the status of surgery by using a scientific, experimental approach, dissecting and collecting thousands of specimens and training surgeons such as Edward Jenner.
  • Despite these changes, there was still no understanding that germs cause disease, so treatments remained limited and many people relied on home remedies, wise women and apothecaries.

Old Cures and New: Treating Disease in the Early Modern Period

Between 1500 and 1800, the Renaissance had changed how educated people thought about the body, but everyday treatment of disease changed much more slowly. Most people were still treated with the same traditional methods as their medieval ancestors.

Traditional treatments that continued:

  • Herbal remedies prepared at home or by an apothecary.
  • Bleeding and purging, still based on the old idea of balancing the humours.
  • Care from family, "wise women" and local healers.

What was new:

  • Exploration brought new ingredients to Europe. The most important was cinchona bark (also called Peruvian or "Jesuit's" bark), which contains quinine and genuinely helped against fever and malaria. Other imports included tobacco, rhubarb and opium.
  • Ideas spread more widely thanks to printing.

So this period is a mix of continuity and change: real progress in knowledge, but slow change in the medicines ordinary people actually received.

Quackery: Medicine for Profit

One striking feature of the 1600s and 1700s was the rise of quackery — the selling of useless or fraudulent treatments by untrained people.

  • Quacks travelled from town to town or advertised in newspapers, promising to cure almost anything.
  • They sold patent medicines: ready-made remedies with secret ingredients and bold claims.
  • These medicines were usually worthless and sometimes harmful, often containing little more than alcohol, sugar or dangerous substances.

Quackery grew because there was no effective regulation, many people could not afford a physician, and there was still no understanding of what caused disease — so it was hard to prove a cure did not work.

Quackery is a useful example of continuity: despite the "beginnings of change", much popular medicine was still ineffective, and the factor of communication (newspapers and advertising) here helped spread bad ideas, not just good ones.

The Great Plague of 1665: Progress in Response?

Plague returned to London in a serious outbreak in 1665, known as the Great Plague. Comparing it with the Black Death of 1348–49 shows how much — and how little — had changed.

FeatureBlack Death (1348–49)Great Plague (1665)
Known true cause?NoNo — still blamed on miasma and God
Believed causesGod, miasma, planetsGod, miasma, "bad air"
Government responseAlmost noneMore organised (see below)
Some useless "cures"Flagellants, bleedingCharms, tobacco, plague doctors

The big change was government action. During the Great Plague, authorities:

  • Ordered quarantine, shutting up infected houses and marking them with a red cross.
  • Banned large public gatherings and closed theatres.
  • Ordered the killing of cats and dogs (which, ironically, may have let the rat population grow).
  • Appointed searchers to record deaths.

The cause was still unknown, so the response could not truly stop the plague, but the stronger role of government marks a real difference — a key example of the government factor beginning to grow.

Hospitals: From Care to Treatment

The idea of a hospital also changed. Medieval hospitals, run by the Church, focused on care — rest, food, warmth and prayer — rather than curing illness. From around 1700, this began to shift.

  • Many new voluntary hospitals were built, funded by wealthy charity rather than the Church.
  • Their focus moved towards treating patients, not just caring for them.
  • Hospitals became places of teaching and training for surgeons and physicians.
  • Specialist hospitals appeared, including hospitals for the "insane" (such as Bethlem, known as "Bedlam") and, later, for children.

The hospital changed from a religious refuge into a place of treatment, learning and training — a clear sign of the "beginnings of change", and a shift from the factor of religion towards science and charity.

Alongside this, the training and status of surgeons and physicians slowly rose, setting the scene for individuals like John Hunter.

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John Hunter: Making Surgery Scientific

John Hunter (1728–1793) is the named individual for this part of the course. He did more than perhaps anyone in 18th-century Britain to raise the status of surgery and make it more scientific.

His contribution:

  • He used a rigorous scientific, experimental method — observe, test, record — rather than relying on tradition.
  • He carried out huge numbers of dissections and built a collection of around thousands of anatomical specimens for study and teaching.
  • He wrote respected books based on careful observation.
  • He trained a new generation of surgeons, most famously Edward Jenner, who went on to develop the smallpox vaccination.

Hunter helped turn surgery from a low-status trade (long linked with barbers) into a respected, evidence-based profession. He is a strong example of the individual and of science and technology as factors of progress.

(Extra context — not required by the 8145 spec, but useful: Hunter is sometimes linked to the grim trade in stolen corpses for dissection, which reminds us that anatomy teaching in this period was controversial as well as scientific.)

Common Exam Mistakes

1. Overstating how much treatment improved

Knowledge and hospitals improved, but everyday treatment stayed limited because germ theory did not yet exist. Strong answers balance genuine change against important continuity.

2. Confusing the Great Plague (1665) with the Black Death (1348–49)

They are different outbreaks. The key contrast for the exam is that by 1665 the government acted far more (quarantine, shut-up houses, killing cats and dogs), even though the true cause was still unknown.

3. Treating quackery as a minor detail

Quackery is a spec point. It shows that popular medicine remained ineffective and that communication (advertising, newspapers) could spread bad ideas as easily as good ones.

4. Misremembering John Hunter

Hunter is important for making surgery scientific and respected and for training Jenner. He did not discover germs or invent vaccination himself.

5. Describing rather than analysing

For the significance question (worth 8 marks on Paper 2), do not just list what changed. Explain why it mattered — for example, why the shift from care to treatment in hospitals was significant for the future of medicine.

Key terms

Quackery
The selling of useless or fraudulent medicines and treatments by untrained people making exaggerated claims to cure disease.
Patent medicine
A ready-made remedy sold to the public, often by quacks, with secret ingredients and bold but false claims.
The Great Plague
A serious outbreak of plague in London in 1665, met with quarantine and other government measures.
Voluntary hospital
A hospital funded by charity and wealthy donors, many of which were built in Britain in the 18th century to treat the sick poor.
Apothecary
A person who prepared and sold medicines and often gave medical advice, cheaper than a physician.
John Hunter
An 18th-century surgeon (1728–1793) who promoted a scientific, experimental approach to surgery and trained Edward Jenner.

Frequently asked questions

Most treatment stayed traditional: herbal remedies, bleeding and purging, based on old ideas about the humours. New ingredients from exploration, such as cinchona bark for fevers, appeared, and 'quacks' sold useless patent medicines with big claims. There was still no idea that germs caused disease.

The Great Plague was a major outbreak of plague in London in 1665. People still did not know the true cause, but the government acted more firmly than during the Black Death, ordering quarantine, shutting up and marking infected houses, banning large gatherings and killing cats and dogs.

John Hunter (1728–1793) helped make surgery more scientific and respected. He studied anatomy through dissection, collected thousands of specimens, insisted on careful observation and experiment, and trained a new generation of surgeons, including Edward Jenner.

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